The International Gamma Knife Research Foundation consists of academic and clinical centers of excellence where brain Stereotactic Radiosurgery is performed using the Leksell Gamma Knife. All participating centers have a track record of outcomes research and participation in clinical trials.
The primary goal of the IGKRF is to facilitate retrospective and prospective clinical trials and outcomes analysis that evaluate the role of Gamma Knife radiosurgery in a wide spectrum of clinical indications.
Because individual centers may evaluate only a small number of patients with rare conditions, pooling of information is critical to evaluate and to improve outcomes. Each center has a professional team consisting of one or more neurological surgeons, radiation oncologists, and medical physicists. Participation is by invitation of the Board of Directors.
The IGKRF is a non-profit scientific, educational, and research entity incorporated in the state of Pennyslvania.
The NAGKC Becomes the IGKRF
Five years ago, 10 centers in the United States and Canada banded together to form the North American Gamma Knife Consortium in order to build the outcome analysis portfolio for multiple indications where stereotactic radiosurgery has shown promise, potential, and long-term effectiveness.
Two common features of each participating center was the use of the same radiosurgical technology and the individual commitment of centers to clinical outcomes research.
The consortium first concentrated on evaluating pooled retrospective outcomes data for less common indications. More than 10 publications emerged. More recently, the consortium developed funding for two prospective clinical trials.
The NAGKC was incorporated as a not–for-profit entity in the State of Pennsylvania and the coordinating center was established in Pittsburgh. In recognition of its expanding membership—which by 2015 reached 23 centers—the value of greater international ties, and the legal foundation character of this non-profit, the board of directors of the NAGKC voted to change the name to the International Gamma Knife Research Foundation.